Dr. Tee SP graduated from University of Malaya with Bachelor of Medicine and Bachelor of Surgery (MBBS) in 1982. He then performed his specialization training in O&G at Seremban General Hospital, University Kebangsaan Malaysia and finally at John Radcliffe Hospital, University of Oxford and was admitted as a member of the Royal College of Obstetricians and Gynaecologists in 1989 and later as a Fellow of the Royal College of Obstetricians and Gynaecologists (FRCOG).
His passion in assisted reproductive technology and fertility treatment led him to pursue his training locally and in National University of Singapore. He qualified with postgraduate Diploma in Reproductive Medicine from the National Population & Family Development Board, Malaysia (LPPKN) in collaboration with Johns Hopkins’ Programme for international Education in O&G, Bachelor of Science in Computing (Hons) from University of Portsmouth, UK and Master of Business Administration from University Tunku Abdul Rahman, Malaysia.
He is one of the pioneer fertility specialists in Malaysia and established Metro IVF Centre in Klang in 1999 and the first IVF pregnancy was delivered in 2000. In 2008, Dr. Tee is one of the key initiators for IVF collaboration between private and public health institutions including Hospital Tengku Ampuan Rahimah, (Metro HTAR IVF Shared Care Programme) and with UiTM (Metro UiTM Private Specialist Centre IVF Shared Care Programme).
With over 20 years of experience in IVF, Dr. Tee has led Metro IVF and it’s group of medical professionals in achieving internationally recognised success rates. The group has since expanded to 7 branches nationwide and was publicly listed in February 2018 on Bursa Malaysia.
Dr. Tee is presently the fertility specialist at Metro IVF and clinical assistant professor at Faculty of Health Science & Medicine at University of Tunku Abdul Rahman (UTAR) and also the treasure and president elect of the Malaysian Society for Assisted Reproductive Technology (MSART).
Dr. Tee SP graduated from University of Malaya with Bachelor of Medicine and Bachelor of Surgery (MBBS) in 1982. He then performed his specialization training in O&G at Seremban General Hospital, University Kebangsaan Malaysia and finally at John Radcliffe Hospital, University of Oxford and was admitted as a member of the Royal College of Obstetricians and Gynaecologists in 1989 and later as a Fellow of the Royal College of Obstetricians and Gynaecologists (FRCOG).
His passion in assisted reproductive technology and fertility treatment led him to pursue his training locally and in National University of Singapore. He qualified with postgraduate Diploma in Reproductive Medicine from the National Population & Family Development Board, Malaysia (LPPKN) in collaboration with Johns Hopkins’ Programme for international Education in O&G, Bachelor of Science in Computing (Hons) from University of Portsmouth, UK and Master of Business Administration from University Tunku Abdul Rahman, Malaysia.
He is one of the pioneer fertility specialists in Malaysia and established Metro IVF Centre in Klang in 1999 and the first IVF pregnancy was delivered in 2000. In 2008, Dr. Tee is one of the key initiators for IVF collaboration between private and public health institutions including Hospital Tengku Ampuan Rahimah, (Metro HTAR IVF Shared Care Programme) and with UiTM (Metro UiTM Private Specialist Centre IVF Shared Care Programme).
With over 20 years of experience in IVF, Dr. Tee has led Metro IVF and it’s group of medical professionals in achieving internationally recognised success rates. The group has since expanded to 7 branches nationwide and was publicly listed in February 2018 on Bursa Malaysia.
Dr. Tee is presently the fertility specialist at Metro IVF and clinical assistant professor at Faculty of Health Science & Medicine at University of Tunku Abdul Rahman (UTAR) and also the treasure and president elect of the Malaysian Society for Assisted Reproductive Technology (MSART).
Dr. Tee SP graduated from University of Malaya with Bachelor of Medicine and Bachelor of Surgery (MBBS) in 1982. He then performed his specialization training in O&G at Seremban General Hospital, University Kebangsaan Malaysia and finally at John Radcliffe Hospital, University of Oxford and was admitted as a member of the Royal College of Obstetricians and Gynaecologists in 1989 and later as a Fellow of the Royal College of Obstetricians and Gynaecologists (FRCOG).
His passion in assisted reproductive technology and fertility treatment led him to pursue his training locally and in National University of Singapore. He qualified with postgraduate Diploma in Reproductive Medicine from the National Population & Family Development Board, Malaysia (LPPKN) in collaboration with Johns Hopkins’ Programme for international Education in O&G, Bachelor of Science in Computing (Hons) from University of Portsmouth, UK and Master of Business Administration from University Tunku Abdul Rahman, Malaysia.
He is one of the pioneer fertility specialists in Malaysia and established Metro IVF Centre in Klang in 1999 and the first IVF pregnancy was delivered in 2000. In 2008, Dr. Tee is one of the key initiators for IVF collaboration between private and public health institutions including Hospital Tengku Ampuan Rahimah, (Metro HTAR IVF Shared Care Programme) and with UiTM (Metro UiTM Private Specialist Centre IVF Shared Care Programme).
With over 20 years of experience in IVF, Dr. Tee has led Metro IVF and it’s group of medical professionals in achieving internationally recognised success rates. The group has since expanded to 7 branches nationwide and was publicly listed in February 2018 on Bursa Malaysia.
Dr. Tee is presently the fertility specialist at Metro IVF and clinical assistant professor at Faculty of Health Science & Medicine at University of Tunku Abdul Rahman (UTAR) and also the treasure and president elect of the Malaysian Society for Assisted Reproductive Technology (MSART).



Blastocyst
Culture






A blastocyst is an embryo that has advanced to the five-day stage which consists of 50-200 cells. Its structure is more complex than the earlier embryo stages as it organized itself into two types of cells, the trophectoderm (which gives rise to the placenta and extra-cellular tissue) and inner cell mass (which gives rise to the fetus). At the center, there is a blastocyst cavity that is filled with fluid (see video). This is a stage that the embryo must achieve before it can embed and implant into the uterine wall.
While the majority of fertilized eggs will develop into a two-day-old embryo (4 cells), only the strongest and healthiest embryos will develop into a blastocyst. Therefore, blastocysts are considered to be a more “select” group of embryos with a higher chance of implantation. In addition, blastocyst transfer provides better coordination between the embryo and the uterus by putting the embryo back in the right place (the uterus) at the right time (blastocyst stage).
Thus, pregnancy rates of five-day embryo transfer (blastocyst) are higher than that of two-day embryo transfer (4-cell-stage). The window of implantation of the blastocyst is five to six days after oocyte pick-up. However, blastocyst culture has a significantly increased risk of no embryo transfer due to the arrest of embryonic development before reaching the blastocyst stage.
Blastocyst transfer is not an option for all IVF patients. It is not suitable when there are less than three viable good quality embryos available. The technique is most successful with patients who are younger and have a large number of eggs available at retrieval. The indications of blastocyst culture are:
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Repeated unsuccessful IVF cycles
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Preimplantation genetic diagnosis (PGD)
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Single embryo transfer to avoid multiple pregnancy